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Effectiveness of Hexetidine 0.1% in Eliminating Candida albicans Colonizing Dentures: A Randomized Clinical In Vivo
Georges Aoun1, Ibrahim Nasseh2, Maria Saadeh3
1Assistant Professor, Department of Oral Pathology and Diagnosis, School of Dentistry, Lebanese University, Beirut, Lebanon.
Background:
Effective cleaning of dentures is important to maintain a good oral hygiene for patients suffering from denture stomatitis (DS). This study aimed to evaluate the efficacy of hexetidine 0.1% in eliminating C. albicans colonizing dentures.
Materials And Methods:
A total of 40 denture wearers (18 men, 22 women; age range 40-80 years) with clinical evidence of DS were randomly divided into 2 groups, 1 test, and 1 control. The dentures of the test group were treated by immersion in hexetidine 0.1% while those of the control group were immersed in distilled water. Swab samples from the palatal surfaces of the upper dentures were collected before and after of cleaner use and examined mycologically.
Results:
Reduction in the number of colony-forming units (CFU) of C. albicans after immersion of the dentures with hexetidine 0.1% was evaluated compared to those of the control group.
Conclusion:
Hexetidine 0.1% solution tested for the first time as a product of disinfection of the acrylic dentures showed average results after immersion of 8 night hours for 4 days.
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