Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Clot Retraction and Fibrinolysis

Clot Retraction and Fibrinolysis

After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.

Mismatch Repair

Mismatch Repair

Mismatch Repair

Mismatch Repair

Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...

Mismatch Repair

Mismatch Repair

Proofreading

Proofreading

Proofreading

Proofreading

Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore, it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Artificial intelligence enables scale, consistency, and rigor in forensic identity inference.

Croatian medical journal·2026

Same author

Terminology, retrieval bias, and field definition in forensic genetic genealogy.

Forensic science international. Synergy·2026

Same author

Large-scale analysis of DNA quantification metrics and SNP sequencing performance in unidentified human remains.

Forensic science international. Genetics·2026

Same author

Othram maps: a graph-powered platform for pedigree visualization and forensic intelligence.

Bioinformatics (Oxford, England)·2026

Same author

On the uncertainty associated with using a signal detection theory model to analyze data from forensic black-box studies.

Forensic science international·2026

Same author

Animal Species and Identity Testing: Developments, Challenges, and Applications to Non-Human Forensics.

Genes·2025

Same journal

Commentary on: Maskell PD, de Korompay A. Letter to the Editor-The transition point from zero-order to first order in blood alcohol elimination curves. Where is it? J Forensic Sci. 2025;70 (1):398-400. https://doi.org/10.1111/1556-4029.15650.

Journal of forensic sciences·2026

Same journal

A novel relationship between time offsets in capillary electrophoresis and DNA sequence variations in short tandem repeats.

Journal of forensic sciences·2026

Same journal

A 4-zone model to determine fentanyl overdose probability.

Journal of forensic sciences·2026

Same journal

Authors' response.

Journal of forensic sciences·2026

Same journal

Determining the utility of radio frequency identification (RFID) technology for disaster victim identification (DVI).

Journal of forensic sciences·2026

Same journal

Stakeholders' perspectives on integrating point-of-care diagnostics into forensic death investigations in South Africa.

Journal of forensic sciences·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 6, 2026

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy

Published on: June 16, 2022

Erratum

Tamyra R Moretti¹, Bruce Budowle², John S Buckleton³

¹DNA Support Unit, Federal Bureau of Investigation Laboratory, Quantico, VA.

Journal of Forensic Sciences

|July 31, 2015

Summary

No abstract available in PubMed .

More Related Videos

Reconstitution Of β-catenin Degradation In Xenopus Egg Extract

Reconstitution Of β-catenin Degradation In Xenopus Egg Extract

Published on: June 17, 2014

Surgical Correction for Pediatric Epiblepharon and Trichiasis

Surgical Correction for Pediatric Epiblepharon and Trichiasis

Published on: July 8, 2025

Related Experiment Videos

Last Updated: Apr 6, 2026

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy

Published on: June 16, 2022

Reconstitution Of β-catenin Degradation In Xenopus Egg Extract

Reconstitution Of β-catenin Degradation In Xenopus Egg Extract

Published on: June 17, 2014

Surgical Correction for Pediatric Epiblepharon and Trichiasis

Surgical Correction for Pediatric Epiblepharon and Trichiasis

Published on: July 8, 2025