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Ana Carolina Da Silva Santos1, Josias Rodrigues2

  • 1Laboratory of Medical Bacteriology, Department of Microbiology and Immunology, Institute of Biosciences of the State University of São Paulo (IBB-UNESP), Botucatu SP, Brazil.

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Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...
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