Biofunctional Materials Based on Amino Cellulose Derivatives--A Nanobiotechnological Concept

This feature article summarizes recent developments in the field of so-called aminodeoxy cellulose derivatives ("amino celluloses") that are applied for functional surface coating of biofunctional materials. After introducing common manufacturing methods for nanostructurized substrates (material surfaces and nanoparticles) biorelevant amino celluloses are described. It could be demonstrated that cellulose is a unique starting material for chemical modification of hydroxyl groups and the adjacent carbon atom. Amino celluloses are proved to be the modifiable polymer of choice for the biofunctionalization of material surfaces. Amino celluloses possess self assembling properties and may form monolayer composites on a variety of substrate materials.