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Related Concept Videos

Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

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Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
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Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

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Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
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Kidney Transplant III: Nursing Management01:16

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Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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Kidney Transplant II: Surgical Procedure01:26

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Dialysis01:27

Dialysis

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Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
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Kidney Transplant I: Introduction01:28

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Updated: Apr 6, 2026

Murine Kidney Transplant Technique
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[Renal replacement therapies – Past, present and future].

Robert M Kalicki1, Sibylle Eicken, Suzan Dahdal

  • 11 Universitätsklinik für Nephrologie, Hypertonie und Klinische Pharmakologie, Inselspital, Universität Bern.

Therapeutische Umschau. Revue Therapeutique
|August 1, 2015
PubMed
Summary

Early nephrologist consultation is crucial for patients with kidney failure. Timely evaluation allows personalized planning for renal replacement therapy (peritoneal dialysis or hemodialysis), improving outcomes and avoiding risks associated with late referrals.

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Area of Science:

  • Nephrology
  • Artificial Organ Replacement

Context:

  • Extracorporeal renal replacement therapy represents a significant advancement in artificial organ technology.
  • Modern renal replacement therapy includes peritoneal dialysis and hemodialysis, offering patients choices for kidney failure management.

Purpose:

  • To trace the historical evolution of renal replacement therapy.
  • To discuss current state-of-the-art peritoneal dialysis and hemodialysis methods.
  • To explore future directions and unresolved questions in the field.

Summary:

  • Patients with failing kidneys have treatment options, but require early nephrologist involvement (at least six months prior) for optimal method selection.
  • Late referral for renal replacement therapy increases mortality, necessitates risky central venous access, and precludes preemptive living kidney donation.
  • Patients with late referrals often require in-center treatment and are less likely to adapt to home or self-care dialysis modalities.

Impact:

  • Highlights the critical importance of timely nephrological care for end-stage renal disease patients.
  • Emphasizes the benefits of informed patient choice and preemptive transplantation.
  • Underscores the risks associated with delayed initiation of renal replacement therapy.