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Russula subnigricans Poisoning: From Gastrointestinal Symptoms to Rhabdomyolysis
Shide Lin1, Maoyuan Mu1, Fangwan Yang1
1Department of Infectious Diseases, First Affiliated Hospital of Zunyi Medical College, Zunyi, China (Dr Lin, Ms. Mu, and Mr F Yang).
Abstract:
Wild mushroom poisoning is often reported to cause acute liver or renal failure. However, acute rhabdomyolysis caused by wild mushroom poisoning has rarely been reported. We describe 7 patients of 1 family with Russula subnigricans Hongo poisoning. Their clinical manifestations varied from gastrointestinal symptoms to rhabdomyolysis, with 1 fatality. Our report provides supporting evidence that rhabdomyolysis may result from ingestion of R subnigricans mushrooms. A key to survival for patients with rhabdomyolysis caused by R subnigricans poisoning may be early recognition and intensive supportive care.
Insights
Wild mushroom poisoning, specifically from Russula subnigricans, can cause rhabdomyolysis, a rare but serious condition. Early recognition and supportive care are crucial for survival in these poisoning cases.
Area of Science:
- Toxicology
- Mycology
- Clinical Medicine
Background:
- Wild mushroom ingestion is a known cause of toxic syndromes.
- Acute liver or renal failure are commonly reported complications.
- Acute rhabdomyolysis is a rarely documented consequence of mushroom poisoning.
Observation:
- A family of 7 individuals experienced poisoning after consuming Russula subnigricans mushrooms.
- Clinical presentations ranged from gastrointestinal upset to severe rhabdomyolysis.
- One fatality occurred within the affected family.
Findings:
- This case series provides evidence linking Russula subnigricans mushroom ingestion to acute rhabdomyolysis.
- The study highlights the varied clinical spectrum of this specific mushroom poisoning.
- Rhabdomyolysis represents a significant and potentially fatal outcome.
Implications:
- Clinicians should consider Russula subnigricans poisoning in patients presenting with rhabdomyolysis, especially with a history of wild mushroom consumption.
- Prompt diagnosis and aggressive supportive management are vital for improving patient outcomes.
- Further research into the specific toxins and mechanisms of Russula subnigricans poisoning is warranted.
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