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Updated: Apr 6, 2026

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit
Published on: April 15, 2021
[Coronary artery aneurysms]
Alessandra Russo1, Luca Favero2, Salvatore Saccà3
1U.O.C. Cardiologia, A.O. San Antonio Abate, Gallarate (VA).
Insights
Coronary artery aneurysms, dilations larger than 1.5 times adjacent segments, are rare but pose diagnostic and treatment challenges. This review covers their causes, mechanisms, clinical features, and therapies based on recent research.
Area of Science:
- Cardiology
- Vascular Medicine
Context:
- Coronary artery aneurysms (CAAs) are uncommon findings in coronary angiography, with reported prevalence varying between 0.3% and 5%.
- The definition involves coronary dilations exceeding 1.5 times the diameter of the adjacent segment.
- Their rarity presents diagnostic and therapeutic dilemmas for clinicians and interventionalists.
Purpose:
- To provide a comprehensive review of coronary artery aneurysms.
- To summarize the latest research on etiologic, pathogenetic, clinical, and therapeutic aspects of CAAs.
- To address the diagnostic and management challenges associated with CAAs.
Summary:
- This review synthesizes current knowledge on coronary artery aneurysms, covering their definition, prevalence, and etiology.
- It details the pathogenesis, clinical presentation, and diagnostic approaches for CAAs.
- The latest therapeutic strategies and follow-up recommendations for patients with CAAs are discussed.
Impact:
- Enhances understanding of coronary artery aneurysms for improved clinical decision-making.
- Provides a valuable resource for cardiologists and interventionalists managing CAAs.
- Contributes to the advancement of patient care through updated research synthesis.
Abstract:
Coronary artery aneurysms are defined as coronary dilations as greater than 1.5 times the largest diameter of the adjacent coronary segment. They are a relatively rare finding on coronary angiography, with prevalence ranging from 0.3% to 5% depending on case series. The identification of a coronary artery aneurysm is often a dilemma for both the clinician and the interventionist in terms of diagnosis, treatment and follow-up. This review summarizes the etiologic, pathogenetic, clinical and therapeutic aspects of coronary artery aneurysms in the light of the latest research on this topic.
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Aneurysm I: Introduction
Coronary Artery Disease I: Introduction
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Aneurysm III: Interprofessional Care
Coronary Artery Disease II: Pathophysiology
Coronary Artery Disease III: Clinical Manifestations

