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Related Experiment Video

Updated: Apr 6, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
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Relationship between depression and chronic periodontitis.

Shiyamali Sundararajan1, Santhanakrishnan Muthukumar1, Suresh Ranga Rao1

  • 1Department of Periodontics, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India.

Journal of Indian Society of Periodontology
|August 1, 2015
PubMed
Summary
This summary is machine-generated.

This study found a direct link between periodontal disease and depression. Patients with periodontitis reported higher depression scores, indicating a significant correlation between oral health and mental well-being.

Keywords:
Chronic periodontitisdepressionprobing depth and clinical attachment loss

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Area of Science:

  • Oral Health and Medicine
  • Psychiatry and Mental Health

Background:

  • Periodontitis is a chronic inflammatory disease affecting tooth-supporting structures.
  • Depression, a common mental disorder, is linked to poor oral hygiene and immune system alterations.
  • Non-oral risk factors, including depression, contribute to chronic periodontitis development.

Purpose of the Study:

  • To investigate the association between clinical periodontal parameters and depression levels.
  • To compare depression ratings in periodontitis patients versus healthy controls.

Main Methods:

  • A case-control study involving 35 patients in each group (periodontitis and control).
  • Periodontal assessment included probing depth and clinical attachment loss measurements.
  • Depression was quantified using Beck's Depression Inventory.

Main Results:

  • Periodontitis patients exhibited significantly higher total depression scores compared to the control group.
  • Beck's Depression Inventory scores were notably elevated in individuals with periodontitis.

Conclusions:

  • A direct correlation exists between the severity of periodontal disease and the severity of depression.
  • Findings suggest a bidirectional relationship or shared underlying mechanisms between periodontitis and depression.