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[An infant with an asymmetric mouth when crying or laughing]

Hanaâ Benjeddi1, Olivier Weijer, Jan Maarten Cobben

  • 1Flevoziekenhuis, afd. Kindergeneeskunde, Almere.

Nederlands Tijdschrift Voor Geneeskunde
|August 1, 2015
PubMed

Insights

Asymmetrical crying in infants can indicate nerve issues or muscle defects. Further investigations are crucial to rule out genetic syndromes and associated organ anomalies.

Area of Science:

  • Pediatric Medicine
  • Clinical Genetics
  • Developmental Biology

Background:

  • Asymmetrical crying in infants may signal nerve compression or facial muscle developmental defects.
  • A 22q11 deletion syndrome is a potential cause, often involving multiple organ systems.

Observation:

  • A 2-month-old infant presented with an asymmetrical mouth when crying or laughing, with no other symptoms.
  • Genetic testing and ultrasounds were performed to rule out 22q11 deletion syndrome.

Findings:

  • Genetic and ultrasound investigations revealed no significant findings for 22q11 deletion syndrome.
  • The infant's condition was diagnosed as isolated asymmetric crying facies due to hypoplasia of the depressor anguli oris muscle.

Implications:

  • An asymmetrical mouth in infants necessitates further investigation to exclude underlying genetic syndromes.
  • Early identification and evaluation are essential for managing potential multi-organ anomalies associated with asymmetric crying facies.
Abstract

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