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Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
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Identification of Risk Factors for Arrhythmia Post Transcatheter Closure of Perimembranous Ventricular Septal Defect

Yifei Li, Yimin Hua, Jie Fang

  • 1Dept. of Pediatric Cardiology, West China Second University Hospital, Sichuan University, No. 20, 3rd section, South Renmin Road, Chengdu, 610041, China. kaiyuzhou313@163.com.

The Journal of Invasive Cardiology
|August 2, 2015
PubMed

Insights

Occluder size, prior arrhythmias, and defect proximity to the tricuspid rim are key risk factors for arrhythmias after perimembranous ventricular septal defect (pmVSD) closure. Careful device selection can minimize complications.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Pediatric Cardiology

Background:

  • Arrhythmias are common after transcatheter closure of perimembranous ventricular septal defects (pmVSD).
  • Identifying independent risk factors for these arrhythmias is crucial for improving patient outcomes.
  • Long-term follow-up data is essential to understand the incidence and predictors of post-procedural arrhythmias.

Purpose of the Study:

  • To identify independent risk factors for arrhythmias following transcatheter closure of pmVSD.
  • To analyze early, continuous, and late onset arrhythmias.
  • To provide insights for reducing post-procedural complications.

Main Methods:

  • Retrospective analysis of 553 patients undergoing pmVSD closure with Amplatzer occluders (June 2003-December 2010).
  • Long-term follow-up (2-8 years) to classify complications as early, continuous, or late.
  • Univariate and logistic regression analyses to identify independent risk factors.

Main Results:

  • Occluder size was an independent risk factor for early, continuous, and late arrhythmias.
  • Preexisting arrhythmias predicted early and late arrhythmias.
  • Proximity of the defect to the tricuspid rim was a risk factor for continuous arrhythmias.

Conclusions:

  • Occluder size, history of arrhythmias, and defect-tricuspid rim distance are significant risk factors for post-pmVSD closure arrhythmias.
  • Appropriate selection of occluder size is critical for minimizing complications.
  • These findings aid in risk stratification and procedural planning.
Abstract

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