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Updated: Apr 6, 2026

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue
Published on: January 11, 2020
3D printer generated thorax phantom with mobile tumor for radiation dosimetry
Rulon Mayer1, Peter Liacouras2, Andrew Thomas3
1Henry Jackson Foundation, Bethesda, Maryland 20817, USA.
A novel anthropomorphic thorax phantom with a moving tumor was developed for accurate radiation dose detection. This phantom enables precise dosimetry within moving tumors and surrounding lung tissue, improving treatment planning.
Area of Science:
- Medical Physics
- Radiotherapy
- Medical Imaging
Background:
- Accurate radiation dose measurement is critical for effective cancer treatment.
- Simulating tumor motion during radiotherapy is essential for precise dose delivery.
- Existing phantoms often lack the ability to accurately represent moving tumors and surrounding tissues.
Purpose of the Study:
- To design, construct, and evaluate an anthropomorphic thorax phantom with a moving surrogate tumor.
- To enable accurate dose detection inside and outside the moving tumor and within surrogate lung tissue.
- To compare measured radiation doses with planned doses for a simulated radiotherapy treatment.
Main Methods:
- A 3D-printed anthropomorphic thorax phantom was created using patient CT scan data.
- A surrogate spherical tumor, controlled by a 3D linear stage, simulated breathing motion.
- Sawdust was used to emulate lung tissue, and radiochromic film was used for dosimetry.
Main Results:
- The phantom accurately simulated patient anatomy and allowed for dose detection in moving and static conditions.
- Gamma analysis showed 8.8% and 5.5% failure rates for moving and static measurements, respectively.
- Calculated dose distributions incorporating tumor motion phase improved agreement between measured and intended doses.
Conclusions:
- The developed anthropomorphic phantom with a moving surrogate tumor is a valuable tool for radiotherapy research.
- It facilitates accurate dose assessment in dynamic treatment scenarios.
- Incorporating tumor motion into dose calculations enhances the accuracy of radiotherapy planning and delivery.
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