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Work Disability in Early Systemic Sclerosis: A Longitudinal Population-based Cohort Study.

Gunnel Sandqvist1, Roger Hesselstrand2, Ingemar F Petersson2

  • 1From the Department of Clinical Sciences, Section of Rheumatology, and Orthopedics, Department of Clinical Sciences, Lund University; Epidemiology and Register Centre South, Skåne University Hospital, Lund, Sweden; Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Denmark.G. Sandqvist, RegOT, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University; R. Hesselstrand, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University; I.F. Petersson, MD, PhD, Orthopedics, Department of Clinical Sciences, Lund University, and Epidemiology and Register Centre South, Skåne University Hospital; L.E. Kristensen, MD, PhD, Department of Clinical Sciences, Section of Rheumatology, Lund University, and Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital. gunnel.sandqvist@med.lu.se.

The Journal of Rheumatology
|August 3, 2015
PubMed
Summary

Systemic sclerosis (SSc) significantly increases work disability within three years of diagnosis. Factors like limited education and prior sickness absence predict sustained work disability in SSc patients.

Keywords:
DISABILITYLONGITUDINAL STUDIESOCCUPATIONAL THERAPYSYSTEMIC SCLEROSISWORK

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Area of Science:

  • Rheumatology
  • Occupational Health
  • Epidemiology

Background:

  • Systemic sclerosis (SSc) is a complex autoimmune disease affecting connective tissues.
  • Understanding work disability (WD) in early SSc is crucial for patient support and economic impact assessment.

Purpose of the Study:

  • To investigate work disability (WD), sick leave, and disability pension in early systemic sclerosis (SSc).
  • To identify risk factors associated with sustained WD in SSc patients.

Main Methods:

  • A longitudinal study of 32 SSc patients in southern Sweden (2003-2009) with 36-month follow-up.
  • Work disability was assessed in 30-day intervals pre- and post-disease onset.
  • Comparisons were made with a general population reference group and stratified by disease/sociodemographic factors.

Main Results:

  • Work disability prevalence increased from 22% at diagnosis to 53% after 3 years.
  • The relative risk for WD in SSc patients compared to the reference group rose from 0.95 at diagnosis to 2.41 after 3 years.
  • WD correlated negatively with years at workplace and education, and positively with pre-onset sickness absence.

Conclusions:

  • A significant increase in work disability occurs within three years of SSc onset.
  • Limited education, fewer years in employment, and prior sickness absence are potential risk factors for persistent WD in SSc.