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Optimization of 3-aryl-3-ethoxypropanoic acids and discovery of the potent GPR40 agonist DS-1558

Rieko Takano1, Masao Yoshida1, Masahiro Inoue2

  • 1Medicinal Chemistry Research Laboratories, Daiichi Sankyo Co., Ltd, 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan.

Bioorganic & Medicinal Chemistry
|August 4, 2015
PubMed

Keywords:
AgonistDS-1558GPR40Glucose-dependentInsulin secretagogues

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