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Total synthesis of astrosterioside A, an anti-inflammatory asterosaponin
1State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, P. R. China. byu@mail.sioc.ac.cn.
Abstract:
Astrosterioside A, a sulfated steroidal hexasaccharide isolated from starfish Astropecten monacanthus showing potent anti-inflammatory activity, was synthesized in a convergent linear sequence of 24 steps and in 6.8% overall yield from adrenosterone.

