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Updated: Apr 6, 2026

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
Published on: April 5, 2017
Primary drug resistance in a region with high burden of tuberculosis. A critical problem
Cecilia Villa-Rosas1, Rafael Laniado-Laborín1, Lorena Oceguera-Palao1
1Clínica y Laboratorio de Tuberculosis, Hospital General de Tijuana, Instituto de Servicios de Salud Pública del Estado de Baja California, Mexicali, Baja California, México.
Objective:
To determine rates of drug resistance in new cases of pulmonary tuberculosis in a region with a high burden of the disease.
Materials And Methods:
New case suspects were referred for drug susceptibility testing.
Results:
28.9% of new cases were resistant to at least one first line drug; 3.9% had a multidrug-resistant strain, 15.6% a monoresistant strain and 9.4% a polyresistant strain.
Conclusion:
Our rate of drug resistant tuberculosis in new cases is very high; this has important clinical implications, since even monoresistance can have a negative impact on the outcome of new cases treated empirically with a six month regimen.
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