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Updated: Apr 6, 2026

A Fluorescence-Based Assay of Membrane Potential for High-Throughput Functional Study of Two Endogenous Ion Channels in Two Epithelial Cell Lines
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A Fluorescence-Based Assay of Membrane Potential for High-Throughput Functional Study of Two Endogenous Ion Channels in Two Epithelial Cell Lines

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Discovery of highly potent, lung-localized epithelial sodium channel inhibitors

Manoj Kumar1, Gustav Welzel1, Arnab K Chatterjee1

  • 1California Institute for Biomedical Research (Calibr), 11119 North Torrey Pines Road, Suite 100, La Jolla, CA 92037, USA.

Bioorganic & Medicinal Chemistry Letters
|August 4, 2015
PubMed

Keywords:
Dimeric pyrazinoylguanidineENaC inhibitorsGuinea pig tracheal potential differenceNon-systemic

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