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Updated: Apr 6, 2026

Monitoring Changes in Human Umbilical Vein Endothelial Cells upon Viral Infection Using Impedance-Based Real-Time Cell Analysis
Published on: May 5, 2023
Pathophysiological Relationship between Infections and Systemic Vasculitis
Carolina Muñoz-Grajales1, Juan C Pineda2
1Rheumatology Department, Pablo Tobón Uribe Hospital, Medellín, Colombia.
Abstract:
The development of autoimmune disorders requires a combination of genetic, immunological, and environmental factors. Infectious agents, such as viruses and bacteria, can trigger autoimmunity through different mechanisms, and for systemic vasculitis in particular, microbial agents have been suggested to be involved in its pathogenesis. Although the exact mechanisms have not been fully elucidated, different theories have been postulated. This review considers the role of infections in the etiology of primary vasculitis, emphasizing their related immunological events.
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