Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Kidney Transplant II: Surgical Procedure

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Matrix and stromal cues cooperatively regulate dormancy-like states of prostate cancer in a dual-niche metastatic model.

Clinical & experimental metastasis·2026

Same author

Gene-body DNA methylation of ONECUT2 predicts its expression and prostate cancer aggressiveness in needle biopsies.

Biomarker research·2026

Same author

Dnmt3a2 expression during embryonic development is required for phenotypic stability.

Communications biology·2025

Same author

Roles of transposable elements and DNA methylation in the formation of CpG islands and CpG-depleted regulatory elements.

Proceedings of the National Academy of Sciences of the United States of America·2025

Same author

Dnmt3a2 expression during embryonic development is required for phenotypic stability.

Research square·2025

Same author

A sustainable and expedited 'One-Stop' prostate cancer diagnostic pathway to reduce environmental impact and enhance accessibility.

BJUI compass·2025

Same journal

Comprehensive bioinformatics and experimental analysis of PPOX reveals its carcinogenic effect in clear cell renal cell carcinoma.

Translational andrology and urology·2026

Same journal

Advancing urological practice: the value of combined antegrade and retrograde ureterography for the management of complex ureteral strictures.

Translational andrology and urology·2026

Same journal

N-acetylcysteine alleviates experimental autoimmune prostatitis in rats by activating PI3K/Akt/CREB and Keap1/Nrf2 pathways.

Translational andrology and urology·2026

Same journal

Analysis of real-world re-induction outcomes with nadofaragene firadenovec in patients with Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle-invasive bladder cancer.

Translational andrology and urology·2026

Same journal

Pulsed Thulium:YAG laser enucleation versus open simple prostatectomy for large-gland benign prostatic hyperplasia: a retrospective comparative observational study.

Translational andrology and urology·2026

Same journal

An intelligent wearable device based on electrical impedance tomography for dynamic and accurate monitoring of voiding function in patients with benign prostatic hyperplasia: protocol for a single-centre self-controlled diagnostic consistency study.

Translational andrology and urology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 6, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

Outlining the limits of partial nephrectomy.

Sameer Chopra¹, Raj Satkunasivam¹, Chandan Kundavaram¹

¹USC Institute of Urology, Catherine & Joseph Aresty Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.

Translational Andrology and Urology

|August 4, 2015

Summary

This summary is machine-generated.

Partial nephrectomy (PN) is standard for renal cell carcinoma (RCC). This review explores PN

Keywords:

Partial nephrectomy (PN)indications limits radical nephrectomy (RN)

More Related Videos

Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma

Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma

Published on: November 22, 2019

Single Port Donor Nephrectomy

Single Port Donor Nephrectomy

Published on: March 12, 2011

Related Experiment Videos

Last Updated: Apr 6, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma

Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma

Published on: November 22, 2019

Single Port Donor Nephrectomy

Single Port Donor Nephrectomy

Published on: March 12, 2011

Area of Science:

Urology
Oncology
Nephrology

Background:

Partial nephrectomy (PN) is the established standard of care for renal cell carcinoma (RCC).
Minimally invasive robotic-assisted approaches have increased the utilization of PN for small renal masses (SRMs).
The oncological limits and applicability of PN are continually being redefined.

Purpose of the Study:

To review the evidence regarding the upper limits of tumour stage for which PN is oncologically safe.
To explore scenarios where PN has limited utility, including complex anatomical and surgical factors.
To discuss the role of molecular biomarkers, particularly epigenetics, in risk stratification for SRMs.

Main Methods:

Comprehensive literature review of studies evaluating partial nephrectomy for renal cell carcinoma.
Analysis of tumour stage, anatomical factors, surgical history, and molecular biomarkers.
Focus on oncological outcomes and risk stratification for small renal masses.

Main Results:

Evidence supports PN for tumours less than pT2a stage.
PN may have a role in select cases of advanced or metastatic RCC.
Factors like prior renal surgery can limit PN utility.

Conclusions:

PN remains a valuable nephron-sparing option for RCC, with evolving indications.
Careful patient selection based on tumour stage, surgical complexity, and emerging biomarkers is crucial.
Epigenetic biomarkers show promise for optimizing SRM risk stratification and treatment selection for PN.