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Universal strategy to engineer catalytic DNA hairpin assemblies for protein analysis

Yanan Tang1, Yanwen Lin2, Xiaolong Yang1

  • 1†Department of Chemistry and Centre for Biotechnology, Brock University, 500 Glenridge Ave., St. Catharines, Ontario, Canada, L2S 3A1.

Analytical Chemistry
|August 4, 2015
PubMed
Summary

Researchers developed protein-responsive catalytic DNA circuits (CDCs) using protein-DNA binders. This innovation enables sensitive detection of protein biomarkers in samples like human serum and cancer cells.

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