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A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Negative work events reported online precede job loss in multiple sclerosis
Seth E Frndak1, Lauren N Irwin1, Victoria M Kordovski1
1Department of Neurology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA; Department of Psychiatry, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.
An online survey accurately predicts job loss in multiple sclerosis (MS) patients. Increased physical disability and negative work events are key indicators, enabling early intervention to prevent unemployment.
Area of Science:
- Neuroscience
- Occupational Health
- Rehabilitation Medicine
Background:
- Multiple sclerosis (MS) significantly impacts employment.
- Predicting job loss in MS patients is crucial for timely support.
- Online surveys offer a scalable method for monitoring vocational health.
Purpose of the Study:
- To validate an online survey for predicting job loss in MS patients.
- To identify risk factors associated with employment termination in MS.
Main Methods:
- 284 individuals (221 MS patients, 63 controls) were monitored quarterly via an online tool.
- Job loss rates were compared between MS patients and controls.
- Survey responses of MS patients who lost jobs were compared to those who remained employed.
Main Results:
- 10% of MS patients experienced job loss, compared to 0% in controls.
- Job loss was associated with later MS diagnosis, progressive disease, and higher physical disability (PDDS).
- Negative work events within three months preceded job loss in declining patients.
Conclusions:
- An online survey effectively monitors physical disability and patient-reported job loss risks in MS.
- This tool can facilitate clinical assessments to prevent unemployment.
- Early detection aids in securing disability benefits for MS patients.

