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Updated: Apr 6, 2026
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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
Published on: August 15, 2019
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Mouse Genome Informatics (MGI): reflecting on 25 years
Janan T Eppig1, Joel E Richardson, James A Kadin
1Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA, janan.eppig@jax.org.
Summary
The Mouse Genome Informatics (MGI) resource integrates mouse genetic and genomic data to aid human disease research. It has evolved with technological advances to become a key bioinformatics resource for biological data.
Area of Science:
- Bioinformatics
- Genomics
- Mouse Models
Background:
- Established in 1989, the Mouse Genome Informatics (MGI) resource aims to integrate genetic, genomic, and biological data for the laboratory mouse.
- The MGI's mission is to facilitate the study of human health and disease by leveraging mouse data.
Observation:
- Major advancements in genetic knowledge, genome sequencing, and mammalian genome manipulation have occurred.
- Biological research and computer technologies have undergone significant paradigm shifts.
Findings:
- MGI has adapted to these changes, becoming an integral part of global bioinformatics infrastructure.
- The resource provides authoritative reference datasets utilized by numerous other bioinformatics platforms.
Implications:
- Understanding MGI's evolution provides insight into current bioinformatics capabilities.
- Future directions in mouse genetics research and bioinformatics infrastructure can be anticipated based on MGI's trajectory.
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