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Updated: Apr 6, 2026
04:23
A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
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Dengue-associated neuromuscular complications.
Ravindra Kumar Garg1, Hardeep Singh Malhotra, Amita Jain
1Department of Neurology, King George Medical University, Lucknow, Uttar Pradesh, India.
Neurology India
|August 5, 2015
Summary
Dengue fever can cause serious neurological issues, including muscle pain, paralysis, and severe rhabdomyolysis. Early diagnosis of these dengue-associated neuromuscular complications is crucial for effective treatment and preventing long-term disability.
Area of Science:
- Neurology
- Infectious Diseases
- Clinical Medicine
Background:
- Dengue virus infection is a significant global health concern.
- Neurological dysfunctions are recognized complications of dengue fever.
- Neuromuscular complications affect up to 4% of dengue patients.
Purpose of the Study:
- To review the spectrum of neuromuscular complications associated with dengue virus infection.
- To highlight the clinical manifestations and diagnostic challenges of these conditions.
- To emphasize the importance of early recognition for timely intervention.
Main Methods:
- Literature review of dengue-associated neurological and neuromuscular disorders.
- Analysis of clinical presentations, including myalgias, myositis, rhabdomyolysis, and paralysis.
- Examination of specific conditions like Guillain-Barré syndrome and mononeuropathies.
Main Results:
- Diffuse myalgia is a common neurological symptom.
- Muscle involvement ranges from myositis to life-threatening rhabdomyolysis.
- Hypokalemic paralysis, Guillain-Barré syndrome, and various neuropathies are significant complications.
Conclusions:
- Dengue virus infection can lead to a diverse range of neuromuscular complications.
- Prompt identification and management of these complications are essential for patient recovery and minimizing disability.
- Further research into pathogenesis and treatment strategies is warranted.
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