Coupling Interval Ratio Is Associated with Ventricular Premature Complex-Related Symptoms
Kyoung-Min Park1, Sung Il Im1, Kwang Jin Chun1
1Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Korean Circulation Journal
|August 5, 2015
Summary
A higher ventricular premature complex (VPC) coupling interval ratio (CI ratio) over 50% predicts VPC-related symptoms like palpitations. This finding may help understand the physiological basis of symptoms in patients with frequent VPCs.
Area of Science:
- Cardiology
- Electrophysiology
- Arrhythmia Research
Background:
- Ventricular premature complexes (VPCs) are common arrhythmias.
- Symptoms associated with VPCs are not well understood.
- Identifying predictors of VPC-related symptoms is crucial for patient management.
Purpose of the Study:
- To identify predictors of symptoms in patients with frequent VPCs.
- To analyze demographic, VPC burden, and electrocardiogram characteristics.
- To correlate VPC surface electrocardiogram features with symptom development.
Main Methods:
- Prospective enrollment of 109 patients with idiopathic outflow tract VPCs.
- Division into symptomatic (Group B) and asymptomatic (Group A) groups.
- Measurement of VPC coupling interval ratio (CI ratio) and other ECG parameters.
Main Results:
- No significant differences in age, daily VPC burden, or VPC origin between groups.
- The VPC CI ratio was significantly higher in the symptomatic group (60% vs. 49%).
- A VPC CI ratio >50% was associated with the presence of symptoms.
Conclusions:
- A higher VPC CI ratio (>50%) is associated with VPC-related symptoms.
- This finding provides a potential electrocardiogram marker for symptom prediction.
- Further research is needed to elucidate the physiological mechanisms.
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