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Published on: December 6, 2016
Review on sedation for gastrointestinal tract endoscopy in children by non-anesthesiologists
Rok Orel1, Jernej Brecelj1, Jorge Amil Dias1
1Rok Orel, Jernej Brecelj, Children's Hospital, University Medical Centre Ljubljana, and Medical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.
Insights
Non-anesthesiologists can use ketamine or benzodiazepine/opioid combinations for pediatric gastrointestinal endoscopy sedation. While propofol is effective, legal restrictions limit its use by non-anesthesiologists.
Area of Science:
- Pediatric Gastroenterology
- Sedation Management
- Endoscopic Procedures
Background:
- Sedation is crucial for pediatric gastrointestinal (GI) endoscopy.
- Non-anesthesiologists frequently administer sedation in this setting.
- Evidence-based recommendations are needed for safe and effective sedation practices.
Purpose of the Study:
- To review evidence on sedation for pediatric GI endoscopy.
- To formulate recommendations for non-anesthesiologists performing these procedures.
- To evaluate different sedation agents and protocols.
Main Methods:
- Systematic literature search of MEDLINE, Cochrane, and EMBASE databases.
- Keywords included "endoscopy, GI", "sedation", and various sedation levels.
- Focus on English-language publications for pediatric age group (2011-2014).
Main Results:
- Propofol offers optimal efficacy and safety but is underutilized by non-anesthesiologists due to legal barriers.
- Ketamine and benzodiazepine/opioid combinations are commonly employed.
- Data on other sedatives, anesthetics, and adjuvant medications were also reviewed.
Conclusions:
- General anesthesia by an anesthesiologist-led team is the preferred approach.
- Sedation teams led by non-anesthesiologists can be an alternative.
- Drug selection must comply with national and institutional regulations.
Aim:
To present evidence and formulate recommendations for sedation in pediatric gastrointestinal (GI) endoscopy by non-anesthesiologists.
Methods:
The databases MEDLINE, Cochrane and EMBASE were searched for the following keywords "endoscopy, GI", "endoscopy, digestive system" AND "sedation", "conscious sedation", "moderate sedation", "deep sedation" and "hypnotics and sedatives" for publications in English restricted to the pediatric age. We searched additional information published between January 2011 and January 2014. Searches for (upper) GI endoscopy sedation in pediatrics and sedation guidelines by non-anesthesiologists for the adult population were performed.
Results:
From the available studies three sedation protocols are highlighted. Propofol, which seems to offer the best balance between efficacy and safety is rarely used by non-anesthesiologists mainly because of legal restrictions. Ketamine and a combination of a benzodiazepine and an opioid are more frequently used. Data regarding other sedatives, anesthetics and adjuvant medications used for pediatric GI endoscopy are also presented.
Conclusion:
General anesthesia by a multidisciplinary team led by an anesthesiologist is preferred. The creation of sedation teams led by non-anesthesiologists and a careful selection of anesthetic drugs may offer an alternative, but should be in line with national legislation and institutional regulations.
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