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Updated: Apr 6, 2026

A Pulmonary Trunk Banding Model of Pressure Overload Induced Right Ventricular Hypertrophy and Failure
Published on: November 29, 2018
Right ventricle failure associated wıth trastuzumab
Nermin Bayar1, Selçuk Küçükseymen2, Sevil Göktaş3
1Cardiology Department, Antalya Education and Research Hospital, Varlık mahallesi, Kazım Karabekir caddesi, Soğuksu-Antalya, Turkey.
Abstract:
Trastuzumab (TZ), a monoclonal antibody against human epidermal growth factor receptor type 2 (HER2), is an important biological agent used for the treatment of positive breast cancer. This paper presents a 46-year-old female patient who developed right heart failure and right ventricular dysfunction while on TZ due to breast cancer, and returned to normal following the discontinuation of the drug. As far as we know, this is the first case report related to a patient presenting with right ventricular dysfunction and induced cardiotoxicity while on TZ.
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