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Updated: Apr 6, 2026

Functional Transcranial Doppler Ultrasound for Monitoring Cerebral Blood Flow
Published on: March 15, 2021
Normal Doppler Reference Values of the Pericallosal Artery.
1Ultrasound Department, Maternity Hospital `Koco Gliozheni`, Tirana, Albania.
This study establishes normal Doppler flow reference values for the fetal pericallosal artery (PCA) across gestation. These findings aid in assessing fetal well-being and detecting hypoxia-related changes.
Area of Science:
- Fetal Medicine
- Neurosonography
- Doppler Ultrasound
Background:
- The pericallosal artery (PCA) is a key cerebral vessel.
- Assessing fetal cerebral hemodynamics is crucial for monitoring fetal well-being.
Purpose of the Study:
- To establish normal reference values for fetal pericallosal artery Doppler flow.
- To correlate these values with gestational age from 18 to 41 weeks.
Main Methods:
- Pulsed Doppler ultrasound was used to evaluate the pericallosal artery (PCA) in 466 normal pregnancies.
- Measurements included the pulsatility index (PI), resistance index (RI), and maximal flow velocity (Vmax) in the A3 and A4 segments.
Main Results:
- The resistance index (RI) showed a plateau until 31 weeks, then decreased. The pulsatility index (PI) plateaued until 36 weeks, then decreased. Maximal flow velocity (Vmax) plateaued until 28 weeks, then slightly increased.
Conclusions:
- Established normal reference values for fetal pericallosal artery Doppler parameters are presented.
- These values can aid clinical judgment in cases of fetal hypoxia and hemodynamic changes.
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