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[Hydro-electrolyte changes induced by transurethral prostatic resection].

P Ponce, R Correia, P Guimarães

    Acta Medica Portuguesa
    |November 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

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    Transurethral resection prostatectomy (TURP) can cause mild hyponatremia from irrigation fluid absorption. This study found serum sodium decreases are common but not clinically significant after TURP.

    Area of Science:

    • Urology
    • Nephrology
    • Surgical Research

    Context:

    • Transurethral resection prostatectomy (TURP) is a common procedure for benign prostatic hyperplasia.
    • Absorption of irrigation fluid (IF) during TURP can lead to severe hyponatremia.
    • Different IFs, such as Sorbitol-Mannitol and distilled water, may have varying effects on serum electrolytes.

    Purpose:

    • To investigate the incidence and clinical significance of hyponatremia following TURP.
    • To compare the effects of Sorbitol-Mannitol IF versus distilled water IF on serum sodium levels.
    • To evaluate electrolyte changes in patients undergoing TURP compared to similar surgical procedures without bladder irrigation.

    Summary:

    • Serum sodium levels decreased significantly in all three groups (Sorbitol-Mannitol IF, distilled water IF, and control group) after the procedure.

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  • The average decrease in serum sodium was 3.4 mEq/l with Sorbitol-Mannitol IF, 2.3 mEq/l with distilled water, and 4.4 mEq/l in the control group.
  • No significant changes in osmolality were observed, and the osmolar gap only increased transiently in the Sorbitol-Mannitol group.

    • Impact:

    • Mild hyponatremia is a common, clinically insignificant finding post-TURP.
    • The degree of hyponatremia observed is comparable to other general surgical procedures not involving bladder irrigation.
    • Hyposmolality is not a significant concern in the context of these TURP procedures and irrigation fluids.