[PERSONALIZATION OF TREATMENT FOR CERVICAL CANCER DURING PREGNANCY]

Area of Science:

• Gynecology
• Oncology
• Maternal-Fetal Medicine

Background:

• Cervical cancer diagnosis during pregnancy presents complex management challenges.
• Balancing oncological treatment with fetal well-being is critical.
• Minimally invasive surgical techniques are evolving for complex cases.

Observation:

• A 29-year-old pregnant patient (16 weeks) diagnosed with stage IIA1 cervical cancer.
• Videoendoscopic pelvic lymph node dissection performed, confirming no lymph node metastasis.
• Patient underwent neoadjuvant chemotherapy (19 & 23 weeks), Cesarean delivery (34 weeks) with radical hysterectomy and ovarian transposition, followed by adjuvant radiotherapy.

Findings:

• The patient achieved a final diagnosis of pT2aN0M0.
• Seven-month follow-up shows the patient is alive with no recurrence.
• The infant shows normal physical and psychomotor development.

Implications:

• This case demonstrates the feasibility of a multidisciplinary approach for managing cervical cancer in pregnancy.
• Aggressive oncological treatment can be integrated with pregnancy continuation.
• Successful outcomes for both mother and child are achievable with careful planning and execution.