Risk Factors for Macrosomia
Elie Nkwabong1, Guilherme Roger Nzalli Tangho2
1Department of Obstetrics & Gynecology, University Teaching Hospital, Yaoundé, Cameroon ; Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, PO Box 1364, Yaoundé, Cameroon.
Objective:
To identify risk factors for macrosomic babies.
Methods:
This cross-sectional analytical study was carried out in the University Teaching Hospital and the Central Hospital of Yaoundé (Cameroon) from October 1st, 2012 to March 31st, 2013. Women who gave birth to ≥4,000 or 3,000-3,499 g babies were recruited. Variables recorded were fetal sex and birth weight, gestational age, maternal age, parity, mother's body mass index (BMI), weight gain during pregnancy, previous macrosomia, and father's BMI. Fisher exact test and student t-test were used for comparison. Level of significance was P < 0.05.
Results:
Main risk factors for macrosomia are delivery of a previous macrosomic baby (OR 13.1), maternal weight gain ≥16 kg (OR 10.2), parity ≥3 (OR 4.8), father's BMI ≥30 (OR 3.7), male sex (OR 2.2), and post-term (OR 1.9).
Conclusion:
Father's obesity should be added among the known risk factors for macrosomia.
Related Concept Videos
01:24Obesity
01:20Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
01:25Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
01:22Diabetes Mellitus: Type 2 and Gestational
01:20Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion
01:24Overview of Lipid Metabolism
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...