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Lower-limb amputation and body weight changes in men.

Alyson J Littman1, Mary Lou Thompson, David E Arterburn

  • 1Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs (VA) Puget Sound Health Care System, Seattle, WA;

Journal of Rehabilitation Research and Development
|August 6, 2015
PubMed
Summary

Lower-limb amputation (LLA) is often followed by significant weight gain, particularly in the first two years post-surgery. Men with transtibial or transfemoral amputation experienced greater weight gain than those with partial foot amputation.

Keywords:
Veteransadultlower-limb amputationmenobesitypartial foot amputationtoe amputationtransfemoral amputationtranstibial amputationweight change

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Area of Science:

  • Rehabilitation Medicine
  • Clinical Research
  • Biomedical Science

Background:

  • The relationship between lower-limb amputation (LLA) and subsequent body weight changes is not well understood.
  • Understanding weight fluctuations post-amputation is crucial for patient health and rehabilitation outcomes.

Purpose of the Study:

  • To investigate and compare longitudinal body weight changes in males following lower-limb amputation versus a non-amputee cohort.
  • To analyze weight change patterns based on the level of amputation (partial foot, transtibial, transfemoral).

Main Methods:

  • Retrospective cohort study utilizing clinical and administrative data from Department of Veterans Affairs facilities.
  • Inclusion of 759 males with LLA (PFA, TTA, TFA) and 3,790 frequency-matched non-disabled controls.
  • Longitudinal tracking of percent weight change for up to 39 months post-baseline.

Main Results:

  • Men with LLA showed significantly greater weight gain in the two years following amputation compared to controls.
  • Transtibial amputation (TTA) and transfemoral amputation (TFA) groups exhibited higher weight gain (8%-9%) than the partial foot amputation (PFA) group (3%-6%).
  • Peak weight gain occurred around the 2-year mark, with some subsequent weight loss observed in the third year.

Conclusions:

  • Lower-limb amputation is frequently associated with clinically significant body weight gain.
  • Further research is necessary to elucidate the underlying causes of this weight gain and to develop effective intervention strategies to mitigate associated health risks.