Related Experiment Video
Updated: Apr 5, 2026

Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
Published on: August 25, 2018
Highly reactive free radicals in electronic cigarette aerosols
Reema Goel1, Erwann Durand2, Neil Trushin3
1Department of Public Health Sciences, Pennsylvania State University Tobacco Center for Regulatory Science (TCORS), Pennsylvania State University College of Medicine , Hershey Pennsylvania 17033, United States.
Abstract:
Electronic cigarette (EC) usage has increased exponentially, but limited data are available on its potential harmful effects. We tested for the presence of reactive, short-lived free radicals in EC aerosols by electron paramagnetic resonance spectroscopy (EPR) using the spin-trap phenyl-N-tert-butylnitrone (PBN). Radicals were detected in aerosols from all ECs and eliquids tested (2.5 × 10(13) to 10.3 × 10(13) radicals per puff at 3.3 V) and from eliquid solvents propylene glycol and glycerol and from "dry puffing". These results demonstrate, for the first time, the production of highly oxidizing free radicals from ECs which may present a potential toxicological risk to EC users.
More Related Videos
09:23A Protocol for Detecting and Scavenging Gas-phase Free Radicals in Mainstream Cigarette Smoke
Published on: January 2, 2012
09:30A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol
Published on: January 18, 2018
Related Concept Videos
Stimulants
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Radical Reactivity: Overview
Radical Autoxidation
Radical Reactivity: Electrophilic Radicals
Bioactivation and Tissue Toxicity
Radical Reactivity: Steric Effects
Along with electronic...