Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

1.5K
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
1.5K
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

769
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
769
Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

969
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
969
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

931
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
931
Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

1.3K
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
1.3K
Cancer Survival Analysis01:21

Cancer Survival Analysis

838
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
838

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Translated article] Is one year follow-up sufficient to assess functional outcomes after rotator cuff repair?

Revista espanola de cirugia ortopedica y traumatologia·2026
Same author

Is one year follow-up sufficient to assess functional outcomes after rotator cuff repair?

Revista espanola de cirugia ortopedica y traumatologia·2026
Same author

Evaluation of the quality of information online for arthroscopic Bankart repair.

Annals of the Royal College of Surgeons of England·2022
Same author

The role of Platelet Rich Plasma and other orthobiologics in bone healing and fracture management: A systematic review.

Journal of clinical orthopaedics and trauma·2022
Same author

Is it safe for patients to drive after intra-articular knee injection?

The Knee·2020
Same author

The majority of patients return to athletic activity following biceps tenodesis.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA·2020

Related Experiment Video

Updated: Apr 5, 2026

Establishment and Histological Analysis of Esophageal Organoids Modeling the Progression from Normal to Cancerous Tissues
05:57

Establishment and Histological Analysis of Esophageal Organoids Modeling the Progression from Normal to Cancerous Tissues

Published on: May 30, 2025

1.2K

Understanding Complete Pathologic Response in Oesophageal Cancer: Implications for Management and Survival.

K E O'Sullivan1, E T Hurley1, J P Hurley1

  • 1The Mater Private Hospital, Eccles Street, Dublin, Ireland.

Gastroenterology Research and Practice
|August 7, 2015
PubMed
Summary

Oesophageal cancer survival remains poor despite treatment advances. This review examines oesophagectomy risks and definitive chemoradiotherapy for oesophageal tumours, exploring treatment options.

More Related Videos

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
11:17

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Published on: February 27, 2026

489
Development of Compendium for Esophageal Squamous Cell Carcinoma
03:36

Development of Compendium for Esophageal Squamous Cell Carcinoma

Published on: April 12, 2024

921

Related Experiment Videos

Last Updated: Apr 5, 2026

Establishment and Histological Analysis of Esophageal Organoids Modeling the Progression from Normal to Cancerous Tissues
05:57

Establishment and Histological Analysis of Esophageal Organoids Modeling the Progression from Normal to Cancerous Tissues

Published on: May 30, 2025

1.2K
Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
11:17

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Published on: February 27, 2026

489
Development of Compendium for Esophageal Squamous Cell Carcinoma
03:36

Development of Compendium for Esophageal Squamous Cell Carcinoma

Published on: April 12, 2024

921

Area of Science:

  • Oncology
  • Surgical Oncology
  • Radiation Oncology

Background:

  • Oesophageal cancer survival rates are poor despite recent improvements.
  • Neoadjuvant chemoradiotherapy followed by oesophagectomy is standard for resectable tumours.
  • Oesophagectomy carries high morbidity and mortality, with complications in up to 60% of patients.

Purpose of the Study:

  • To review current morbidity and mortality associated with oesophagectomy.
  • To examine grading systems for pathological response to treatment.
  • To discuss data from clinical trials on definitive chemoradiotherapy for oesophageal cancer.

Main Methods:

  • Literature review of oesophageal cancer treatment strategies.
  • Analysis of surgical outcomes and complication rates.
  • Evaluation of pathological response grading systems.
  • Synthesis of data from clinical trials on definitive chemoradiotherapy.

Main Results:

  • Oesophagectomy has significant associated morbidity and mortality.
  • Complication rates following oesophagectomy can be as high as 60%.
  • Definitive chemoradiotherapy is an emerging strategy for specific tumour sites.

Conclusions:

  • There is a need to evaluate alternative treatment strategies for oesophageal cancer.
  • Definitive chemoradiotherapy shows promise as an alternative to oesophagectomy for certain patients.
  • Further research is needed to optimize pathological response assessment and treatment protocols.