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Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome
Published on: September 27, 2024
Associations between low levels of serum uric acid and cardiometabolic parameters
Sara Ciarla1, Paolo Giorgini1, Manuela Struglia1
1a University of L'Aquila, Department of Life, Health and Environmental Sciences, San Salvatore Hospital , L'Aquila , Italy.
Introduction:
Elevated serum uric acid (SUA) levels are associated with increased cardiovascular risk.
Objective:
To evaluate the association between SUA levels and cardiometabolic parameters.
Materials And Methods:
SUA levels and metabolic parameters were evaluated in 139 subjects, divided into low (<5 mg/dl) and high SUA group (≥5 mg/dl).
Results:
In low SUA group, SUA levels directly correlated with creatinine, body mass index, waist circumference, blood pressure, glucose and insulin levels, triglyceride and C-reactive protein levels. In high SUA group, SUA levels directly correlated with body weight, triglyceride, C-reactive protein, and inversely correlated with HDL-cholesterol concentrations.
Discussion And Conclusions:
High SUA levels were linked with several cardiometabolic parameters, and low SUA levels were linearly correlated with recognized cardiovascular risk factors. Therefore, increasing SUA levels - even at low concentration - could be associated with higher cardiovascular risk. Thus the range of normality for SUA level should be further analysed.
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