Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The conduction bundle at the atrioventricular junction. An anatomical study.

H Kurosawa1, A E Becker

  • 1Department of Pathology, University of Amsterdam, Academic Medical Center, The Netherlands.

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|January 1, 1989
PubMed
Summary

The atrioventricular junction

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mental health training for secondary school teachers in Haiti: a mixed methods, prospective, formative research study of feasibility, acceptability, and effectiveness in knowledge acquisition.

Global mental health (Cambridge, England)·2017
Same author

Multiple cardiac lipomas and sudden death: a case report and literature review.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology·2015
Same author

The response to percutaneous transluminal coronary angioplasty: An ultrastructural study of smooth muscle cells and endothelial cells.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology·2015
Same author

Specialized membrane contacts between immunocompetent cells in human atherosclerotic plaques.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology·2015
Same author

Ebstein's malformation-What's in a name?

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology·2015
Same author

Ebstein's malformation.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology·2015

Area of Science:

  • Cardiovascular Anatomy
  • Cardiac Electrophysiology

Background:

  • The atrioventricular (AV) junction is critical for cardiac electrical conduction.
  • Variability in its anatomical structure may influence cardiac function and susceptibility to disease.

Purpose of the Study:

  • To investigate the topographical anatomical variability of the conduction bundle within the AV junction in human hearts.
  • To correlate anatomical variations with potential clinical implications.

Main Methods:

  • Serial sectioning of the AV junctional area from four normal human hearts.
  • Three-dimensional reconstruction of the conduction bundle and adjacent structures (trabecula septomarginalis, membranous septum).

Main Results:

  • Significant variability was observed in the extent and ramification of the posterior limb of the trabecula septomarginalis.
  • The conduction bundle's position and coverage by surrounding muscle varied considerably between specimens.
  • One case showed minimal muscle coverage, positioning the bundle centrally and subendocardially.

Conclusions:

  • The topographical anatomy of the AV junction's conduction bundle exhibits substantial inter-individual variability.
  • This variability may predispose the conduction system to mechanical stress, potentially leading to heart block, especially in the elderly.
  • Careful surgical inspection of the AV junction is crucial due to its variable anatomy.

Related Experiment Videos