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Published on: March 7, 2025
Electrospinning of PEGylated polyamidoamine dendrimer fibers
Donald C Aduba1, Jefferson W Overlin1, Chad D Frierson2
1Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA 23284, USA.
Abstract:
Polyamidoamine (PAMAM) dendrimers have emerged as an important class of nanostructured materials and have found a broad range of applications. There is also an ongoing effort to synthesize higher-complexity structures using PAMAM dendrimers as enabling building blocks. Herein, we report for the first time the fabrication of electrospun nanocomposite fibers composed of dendrimer derivatives, namely PEGylated PAMAM dendrimers, blended with a small amount of high-molecular-weight polyethylene oxide (PEO). Morphological features and mechanical properties of the resulting dendrimer fiber mats were assessed.

