Related Experiment Video
Updated: Apr 5, 2026

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
Published on: February 3, 2023
Making the RCT more useful for innovation with evidence-based evolutionary testing
Kevin G Volpp1, C Terwiesch2, A B Troxel3
1Center for Health Equity Research and Promotion, Philadelphia VA Medical Center, USA; Leonard Davis Institute Center for Health Incentives and Behavioral Economics, USA; University of Pennsylvania, School of Medicine, USA; The Wharton School, USA; Penn Medicine Center for Innovation, USA.
Abstract:
We propose a new innovation model designed to accelerate the rate of learning from provider payment reform initiatives. Drawing on themes from operations research, we describe a new approach that balances speed and rigor to more quickly build evidence on what works in delivery system redesign. While randomized controlled trials provide "gold standard" evidence on efficacy, traditional RCTs tend to be static and provide information too slowly given the CMMI tagline of "We can't wait." Our approach speaks to broader needs within health financing and delivery reform for testing that while rigorous recognizes the urgency of the challenges we face.
Related Concept Videos
The Evidence for Evolution
Randomized Experiments
Simple randomization
Simple...
Evolutionary Psychology
Evolution of New Traits in Microbes
Criticisms of the Evolutionary Perspective
Evolutionary psychology provides one explanation for these findings, suggesting...
What is an Experiment?

