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Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
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Substantial Receptor-induced Structural Rearrangement of Rotavirus VP8*: Potential Implications for Cross-Species

Xing Yu1, Rahul Mishra2, Gavan Holloway3

  • 1Institute for Glycomics, Griffith University Gold Coast Campus, Southport, QLD, 4222, Australia. h.blanchard@griffith.edu.au.

Chembiochem : a European Journal of Chemical Biology
|August 8, 2015
PubMed
Summary

Rotavirus VP8* protein undergoes significant structural changes when binding to host cell glycans. This adaptability explains how rotaviruses infect various hosts and aids in understanding animal rotavirus emergence in humans.

Keywords:
carbohydratesreceptor recognitionrotavirusstructural rearrangement

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