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Corticosteroid-induced exophthalmos.

J T Van Dalen1, M D Sherman

  • 1Department of Ophthalmology, University of Arizona College of Medicine, Tucson 85724.

Documenta Ophthalmologica. Advances in Ophthalmology
|August 1, 1989
PubMed
Summary

Corticosteroid therapy can cause exophthalmos (protruding eyes) in patients. This condition, though potentially overlooked, appears more common than previously thought based on a study of 21 individuals.

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Area of Science:

  • Ophthalmology
  • Endocrinology
  • Pharmacology

Background:

  • Sustained corticosteroid therapy is widely used for various medical conditions.
  • Exophthalmos is a known but potentially under-recognized side effect of corticosteroid use.

Purpose of the Study:

  • To investigate the occurrence and characteristics of exophthalmos in patients on long-term corticosteroid treatment.
  • To determine if corticosteroid-induced exophthalmos is a more prevalent condition than previously documented.

Main Methods:

  • A cohort of twenty-one patients receiving sustained corticosteroid therapy and presenting with exophthalmos was identified.
  • Comprehensive ophthalmologic examinations were performed for all patients.
  • Diagnostic tests were conducted to exclude alternative etiologies for exophthalmos.

Main Results:

  • Twenty-one patients on long-term corticosteroid therapy presented with exophthalmos.
  • Ophthalmologic examinations and further testing confirmed corticosteroid-induced exophthalmos in these patients.
  • The findings suggest this condition is more frequent than previously reported in medical literature.

Conclusions:

  • Corticosteroid-induced exophthalmos is a distinct clinical entity.
  • Healthcare providers should consider corticosteroid use as a potential cause of exophthalmos in patients.
  • Increased awareness and recognition of this side effect are warranted in clinical practice.

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