Platelet Transfusions in the Neonatal Intensive Care Unit
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Updated: Apr 5, 2026
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Published on: August 24, 2015
Katherine Sparger1, Emoke Deschmann2, Martha Sola-Visner3
1Department of Pediatrics, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
Abstract:
There is significant world-wide variability in platelet transfusion thresholds used to transfuse thrombocytopenic neonates. A large multicenter randomized controlled trial comparing 2 different platelet transfusion thresholds in neonates is currently ongoing, and should provide data to guide transfusion practice. However, several studies have found that factors other than the degree of thrombocytopenia determine the bleeding risk. Thus, it will be important to develop better tests to assess primary hemostasis and bleeding risk in neonates.
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