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Percutaneous Coronary Intervention for Septic Emboli in the Left Main Trunk as a Complication of Infective
Keiki Sugi1, Shintaro Nakano1, Yusuke Fukasawa1
1Division of Cardiology, International Medical Center, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama 350-1298, Japan.
Insights
Infective endocarditis with acute myocardial infarction is rare but deadly. This case shows successful treatment with percutaneous coronary intervention followed by surgery, highlighting early diagnosis and intervention for better outcomes.
Area of Science:
- Cardiology
- Infectious Diseases
- Cardiac Surgery
Background:
- Infective endocarditis (IE) complicated by acute myocardial infarction (AMI) presents a significant challenge due to its high fatality rate and lack of established treatment guidelines.
- Optimal management strategies for this rare condition remain controversial, necessitating case-based evidence.
Observation:
- A 73-year-old male with IE of the mitral and aortic valves developed AMI with cardiovascular collapse.
- Coronary angiography revealed AMI secondary to septic emboli in the left main coronary artery.
Findings:
- Successful emergent percutaneous coronary intervention (PCI), including aspiration and stent deployment, stabilized the patient's vital signs.
- The patient subsequently underwent successful mitral and aortic valve replacement and debridement with no major postoperative complications.
Implications:
- This case underscores the importance of prompt diagnosis in managing IE-complicated AMI.
- Aggressive PCI can serve as an effective bridge to definitive surgical treatment in hemodynamically unstable patients.
- Further discussion is warranted regarding the optimal treatment strategy for AMI secondary to IE.
Abstract:
Infective endocarditis (IE) complicated by acute myocardial infarction (AMI) is frequently fatal and may require emergent interventions. However, the optimal treatment of this rare condition remains controversial as it lacks established guidelines. We successfully treated a patient with IE complicated by AMI during the acute phase using percutaneous coronary intervention (PCI) followed by surgery. A 73-year-old man was diagnosed with IE of the mitral and aortic valves caused by Streptococcus oralis. Four weeks after the initiation of antibiotics sensitive to the causative bacteria, he suddenly developed AMI manifested by chest pain and dyspnoea with cardiovascular collapse. Emergent coronary angiography revealed that the myocardial infarction was secondary to septic emboli in the left main trunk. Emergent PCI comprising aspiration and stent deployment, was successfully performed, and his vital signs were immediately stabilised. He subsequently underwent mitral and aortic valve replacement and debridement without major post-operative complications. Although the optimal treatment strategy for haemodynamically unstable AMI secondary to IE requires further discussion, the present case indicates the importance of early diagnosis and the potential effectiveness of aggressive PCI as a bridge to the following surgery.
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