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Related Concept Videos

Diffusion01:21

Diffusion

7.3K
Diffusion is a type of passive transport. In passive transport, a substance tends to move from an area of high concentration to an area of low concentration until the concentration is equal across the space. For example, take the diffusion of substances through the air. When someone opens a perfume bottle in a room filled with people, the perfume is at its highest concentration in the bottle and is at its lowest at the edges of the room. The perfume vapor will diffuse, or spread away, from the...
7.3K
Diffusion01:12

Diffusion

230.8K
Diffusion is the passive movement of substances down their concentration gradients—requiring no expenditure of cellular energy. Substances, such as molecules or ions, diffuse from an area of high concentration to an area of low concentration in the cytosol or across membranes. Eventually, the concentration will even out, with the substance moving randomly but causing no net change in concentration. Such a state is called dynamic equilibrium, which is essential for maintaining overall...
230.8K
Facilitated Diffusion01:16

Facilitated Diffusion

1.6K
The plasma membrane, a critical structure in cellular biology, houses an array of transporters, or carrier proteins, interspersed within its lipid bilayer. These proteins play a crucial role in solute transport through facilitated diffusion, a form of passive diffusion that uses transporters to move the molecules across the membrane.
In this process, substrates such as organic compounds and ions interact with a transporter on one side, triggering conformational changes in proteins that enable...
1.6K
Theories of Dissolution: Diffusion Layer Model01:15

Theories of Dissolution: Diffusion Layer Model

2.2K
Dissolution, the process by which drug particles dissolve in a solvent, is explained by the diffusion layer model, a theoretical framework that simulates the absorption of oral drugs and allows us to analyze experimental data.
This process starts with a thin layer, saturated with the drug, forming at the interface between the solid and liquid. The solute then diffuses from this layer into the main solution. The Noyes-Whitney equation suggests that the rate of dissolution relies on the diffusion...
2.2K
Passive Diffusion: Overview and Kinetics01:17

Passive Diffusion: Overview and Kinetics

1.7K
Passive diffusion is a critical process that allows small lipophilic drugs to cross the cell membrane along a concentration gradient. This mechanism's efficiency depends on four primary factors: the membrane's surface area, the drug's lipid-water partition coefficient, the concentration gradient, and the membrane's thickness.
When administered orally, drugs establish a substantial concentration gradient between the gastrointestinal (GI) lumen and the bloodstream, expediting...
1.7K
Drug Distribution: Overview01:11

Drug Distribution: Overview

1.3K
Drug distribution within the body is a dynamic process involving the movement of a drug in two directions across various compartments: from the bloodstream into tissues (tissue uptake) and from tissues back into the bloodstream (tissue release or redistribution). This process is passive and primarily driven by two variables: the concentration gradient between the bloodstream and the extravascular tissues and the drug's ability to cross the cell membrane.
Initially, the free drug in the...
1.3K

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Related Experiment Video

Updated: Apr 5, 2026

The Diffusion of Passive Tracers in Laminar Shear Flow
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The Diffusion of Passive Tracers in Laminar Shear Flow

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Diffusion theory and knowledge dissemination, utilization and integration.

Lawrence W Green1, Judith M Ottoson2, César García3

  • 1University of California at San Francisco.

Frontiers in Public Health Services & Systems Research
|August 8, 2015
PubMed
Summary

Applying evidence-based practice in public health requires community engagement alongside scientific evidence. This approach ensures public health initiatives meet diverse population needs effectively.

Keywords:
disease preventionevidence-based public healthinterventionpopulation-based

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Area of Science:

  • Public Health
  • Health Services Research
  • Community Health

Background:

  • Public health achievements are unevenly distributed across populations.
  • Varied cultures and practice circumstances pose challenges to equitable public health outcomes.

Purpose of the Study:

  • To review concepts for applying evidence-based practice in public health.
  • To address the challenges of varied populations and practice contexts.

Main Methods:

  • Review of key components of evidence-based public health (EBPH).
  • Analysis of traditional emphasis on scientific evidence versus community engagement.
  • Exploration of program planning frameworks and data systems.

Main Results:

  • Evidence-based public health (EBPH) involves scientific evidence, data systems, program planning, community engagement, evaluation, and dissemination.
  • Traditional EBPH often overemphasizes scientific evidence.
  • Community and practitioner engagement is crucial for assessing needs, assets, and circumstances.

Conclusions:

  • Effective evidence-based public health (EBPH) necessitates a balanced approach, prioritizing both scientific evidence and community/practitioner input.
  • Utilizing program planning frameworks and local data enhances the assessment of community needs and circumstances.
  • This integrated approach can lead to more equitable and effective public health interventions.