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Merkel cell carcinoma in a patient with GATA2 deficiency: a novel association with primary immunodeficiency
C Crall1, K W Morley2, G Rabinowits3
1Harvard Medical School, Boston, MA, U.S.A.
The British Journal of Dermatology
|August 8, 2015
Abstract:
A 55-year-old woman with GATA2 deficiency and neurofibromatosis 1 was diagnosed with Merkel cell carcinoma (MCC). This polyomavirus-associated cutaneous malignancy has previously been associated with immunosuppression and acquired immunodeficiencies such as HIV/AIDS. However, MCC has not been previously reported in the setting of underlying primary or inherited immunodeficiency.
