Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Alterations in Blood Pressure01:30

Alterations in Blood Pressure

2.5K
Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
2.5K
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

729
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
729
Blood Pressure Imbalances and Circulatory Shock01:24

Blood Pressure Imbalances and Circulatory Shock

1.9K
Disorders affecting blood volume, vascular tone, or vascular function can disrupt vascular homeostasis, including conditions like hypertension, hemorrhage, and shock.
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...
1.9K
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

4.0K
Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
4.0K
Disorders of the Autonomic Nervous System01:18

Disorders of the Autonomic Nervous System

1.9K
The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's...
1.9K
Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

2.6K
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Procedural predictors of epidural blood patch efficacy in spontaneous intracranial hypotension.

Regional anesthesia and pain medicine·2019
Same author

Penetrating Osseous Spicules Causing High-Flow Ventral CSF Leaks in the Setting of Relatively Low BMI : A Preliminary Study.

Clinical neuroradiology·2017
Same author

Re-evaluating the Incidence of Idiopathic Intracranial Hypertension in an Era of Increasing Obesity.

Ophthalmology·2017
Same author

Erratum to: Efficacy of epidural blood patch with fibrin glue additive in refractory headache due to intracranial hypotension: preliminary report.

SpringerPlus·2016
Same author

Efficacy of epidural blood patch with fibrin glue additive in refractory headache due to intracranial hypotension: preliminary report.

SpringerPlus·2016
Same author

Optic neuropathy secondary to spontaneous intracranial hypotension (SIH) as related to experimental primate model.

Investigative ophthalmology & visual science·2014
Same journal

Key Considerations in Telestroke Program Management.

Continuum (Minneapolis, Minn.)·2026
Same journal

Neurology's Action Potential: Delivering on the Promise of Brain Health.

Continuum (Minneapolis, Minn.)·2026
Same journal

Erratum.

Continuum (Minneapolis, Minn.)·2026
Same journal

Management of Large Artery Atherosclerosis.

Continuum (Minneapolis, Minn.)·2026
Same journal

Thrombolysis, Thrombectomy, and Antithrombotic Therapy for Acute Ischemic Stroke.

Continuum (Minneapolis, Minn.)·2026
Same journal

Stroke in Children and Younger Adults.

Continuum (Minneapolis, Minn.)·2026
See all related articles

Related Experiment Video

Updated: Apr 5, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
09:14

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Published on: June 18, 2021

3.0K

Spontaneous Intracranial Hypotension.

Bahram Mokri

    Continuum (Minneapolis, Minn.)
    |August 8, 2015
    PubMed
    Summary
    This summary is machine-generated.

    Spontaneous intracranial hypotension, often from cerebrospinal fluid (CSF) leaks, presents diverse symptoms and challenges. This review guides neurologists through diagnosis, evaluation, and treatment of this condition.

    More Related Videos

    Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation
    09:01

    Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation

    Published on: October 15, 2021

    8.9K
    Intracranial Pressure Monitoring In Nontraumatic Intraventricular Hemorrhage Rodent Model
    08:18

    Intracranial Pressure Monitoring In Nontraumatic Intraventricular Hemorrhage Rodent Model

    Published on: February 8, 2022

    3.1K

    Related Experiment Videos

    Last Updated: Apr 5, 2026

    Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
    09:14

    Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

    Published on: June 18, 2021

    3.0K
    Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation
    09:01

    Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation

    Published on: October 15, 2021

    8.9K
    Intracranial Pressure Monitoring In Nontraumatic Intraventricular Hemorrhage Rodent Model
    08:18

    Intracranial Pressure Monitoring In Nontraumatic Intraventricular Hemorrhage Rodent Model

    Published on: February 8, 2022

    3.1K

    Area of Science:

    • Neurology
    • Neurosurgery
    • Radiology

    Background:

    • Spontaneous intracranial hypotension (SIH) arises from cerebrospinal fluid (CSF) volume depletion, typically due to spontaneous CSF leaks.
    • Increasing diagnoses of SIH, including atypical and treatment-resistant cases, pose significant challenges for neurologists.

    Purpose of the Study:

    • To provide a comprehensive guide for neurologists on the diagnosis, evaluation, and treatment of SIH.
    • To address the growing complexity and challenges associated with SIH management.

    Main Methods:

    • Review of clinical spectrum, diagnostic imaging, and treatment modalities for SIH.
    • Emphasis on CT myelography as the primary tool for leak localization.
    • Discussion of radioisotope cisternography for uncertain cases.

    Main Results:

    • The clinical presentation and imaging features of SIH are diverse and can differ from post-dural puncture hypotension.
    • Complex CSF leak anatomy, involving connective tissue disorders and dural weaknesses, is common.
    • CT myelography is crucial for leak detection, with dynamic CT for rapid leaks and cisternography for equivocal cases.

    Conclusions:

    • SIH encompasses varied clinical aspects, including headache patterns, CSF alterations, and imaging findings.
    • Understanding the underlying mechanisms and potential complications is vital for effective management.
    • Epidural blood patch remains a primary treatment, with evolving techniques like multilevel injections for specific cases.