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The Incidence and the Risk Factors of Silent Embolic Cerebral Infarction After Coronary Angiography and Percutaneous

Onur Sinan Deveci1, Aziz Inan Celik2, Firat Ikikardes2

  • 1Faculty of Medicine, Department of Cardiology, Cukurova University, Balcali Hospital, Adana, Turkey onurdeveci@yahoo.co.uk.

Angiology
|August 9, 2015
PubMed

Insights

Silent embolic cerebral infarction (SECI) is a complication of coronary angiography (CAG) and percutaneous coronary intervention (PCI). Higher SYNTAX scores predict SECI risk, highlighting the need for consideration after CAG.

Area of Science:

  • Cardiology
  • Neurology
  • Radiology

Background:

  • Silent embolic cerebral infarction (SECI) is a significant complication following coronary angiography (CAG) and percutaneous coronary intervention (PCI).
  • Understanding risk factors for SECI is crucial for patient management and stroke prevention in cardiovascular procedures.

Purpose of the Study:

  • To investigate the incidence and clinical predictors of SECI in patients undergoing CAG with or without PCI.
  • To assess the relationship between coronary artery disease complexity, procedural type, and the occurrence of SECI.

Main Methods:

  • Prospective recruitment of 101 patients with stable coronary artery disease undergoing CAG +/- PCI.
  • Cerebral diffusion-weighted magnetic resonance imaging (DW-MRI) performed within 24 hours post-procedure to detect SECI.
  • Comparison of clinical and angiographic characteristics between patients with and without SECI.

Main Results:

  • SECI was detected in 12% (12/101) of patients.
  • Higher age, total cholesterol, SYNTAX score (SS), and prior coronary artery bypass history were associated with SECI.
  • SECI was more frequent in the PCI group (33.3% vs 5.2%) and significantly associated with higher SS in both CAG and PCI groups.

Conclusions:

  • The SYNTAX score is a significant predictor of SECI risk after CAG and PCI.
  • Increased CAD complexity, as indicated by the SS, elevates the risk of SECI.
  • SECI should be more frequently considered as a potential complication after CAG procedures.

Keywords:
SYNTAX scorecoronary angiographypercutaneous coronary interventionsilent embolic cerebral infarction

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