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Identification of dialkyl diacetylene diols with potent cancer chemopreventive activity

Chang-Yong Lee1, Ji Ho Yun2, Kyungsu Kang2

  • 1College of Pharmacy, Gachon University, 191 Hambakmoe-ro, Yeonsu-gu, Incheon 406-799, Republic of Korea.

Bioorganic & Medicinal Chemistry Letters
|August 9, 2015
PubMed

Keywords:
CancerChemopreventionDiyneQuinone reductaseStereoisomeric

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Compounds bearing two hydroxyl groups are known as diols. When the hydroxyl groups are located on adjacent carbon atoms, the diols are called vicinal diols or glycols. Under acidic conditions, vicinal diols undergo a specific reaction called pinacol rearrangement.
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