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Monitoring medication adherence in multiple sclerosis using a novel web-based tool: A pilot study.

Jill R Settle1, Heidi W Maloni2, McKenzie Bedra3

  • 1Multiple Sclerosis Centers of Excellence, Washington, DC, USA Baltimore Veterans Affairs Medical Centers, USA jill.settle@va.gov.

Journal of Telemedicine and Telecare
|August 9, 2015
PubMed
Summary

A new web-based system, MS Home Automated Telehealth (MS HAT), efficiently monitors multiple sclerosis (MS) medication adherence. This patient-centered tool shows promise for improving adherence tracking and potentially enhancing therapeutic outcomes.

Keywords:
Multiple sclerosismedication adherencemonitoringtelehealth

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Area of Science:

  • Neurology
  • Health Informatics
  • Pharmacology

Background:

  • Medication non-adherence in multiple sclerosis (MS) is prevalent, leading to significant costs and reduced therapeutic benefits.
  • Current methods for monitoring adherence are often time-consuming and expensive for healthcare providers.
  • A need exists for efficient and patient-centered tools to track medication adherence in MS patients.

Purpose of the Study:

  • To evaluate the effectiveness of the MS Home Automated Telehealth (MS HAT) system in monitoring medication adherence in patients with MS.
  • To compare adherence monitoring using the MS HAT system versus routine care.
  • To explore the correlation between different adherence monitoring modalities.

Main Methods:

  • A randomized controlled trial involving 30 participants with MS.
  • Participants were assigned to either routine care or the MS HAT system for six months.
  • Adherence to weekly interferon beta-1a intramuscular injections and daily vitamin D was tracked using self-reports, diaries, pharmacy refills, serum levels, and MS HAT alerts.

Main Results:

  • Weekly interferon beta-1a intramuscular adherence showed high correlation across multiple tracking methods.
  • Vitamin D adherence consistency varied across the different monitoring modalities.
  • The MS HAT system enabled efficient, patient-centered adherence monitoring for healthcare providers, reducing reliance on chart reviews and phone calls.
  • Patients with better cognitive function appeared to benefit more from the MS HAT system.

Conclusions:

  • The MS Home Automated Telehealth (MS HAT) system is a promising tool for efficiently monitoring medication adherence in multiple sclerosis patients.
  • The system facilitates patient-centered care and may improve adherence tracking compared to traditional methods.
  • Further research is warranted to investigate the system's effects on different medications and patient populations, particularly concerning cognitive function.