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Updated: Apr 5, 2026

Scratch Migration Assay and Dorsal Skinfold Chamber for In Vitro and In Vivo Analysis of Wound Healing
Published on: September 26, 2019
Do not scratch that mole!
Mark Jelcic1, Philipp Niethammer1
1Cell Biology Program, Memorial Sloan Kettering Cancer Center, 411 E 67th Street, New York, NY 10065, USA.
Abstract:
Nevi harbor some of the same oncogene mutations that also drive malign melanoma. Further tumor promoting events are required to unleash their carcinogenic potential. Using zebrafish whose melanocytes overexpress an HRAS-oncogene, a new study reports that injury induces melanoma, possibly through recruitment of neutrophils that trigger proliferation of preneoplastic melanocytes.
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