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Updated: Apr 5, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
Published on: November 3, 2010
[ASSOCIATION OF ALLELE VARIANTS OF RECEPTOR GENE OF ANDROGENS (BY THE NUMBER OF CAG-REPEATS) WITH ANDROGEN DEPENDENT
Abstract:
This review discusses up-to-date conceptions concerning an association of androgen receptor gene (AR) allele (by the number of CAG-repeats) variations with the change of the receptor activity in humans. Different contradictory experiment results concerning the AR function dependence on the number of CAG-repeats have been analyzed. The authors discuss this problem paying mostly their attention to the interrelation between the number of CAG-repeats and indicators of glucose and lipid metabolism in males and females.
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