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Updated: Apr 5, 2026
Preparation and Characterization of SDF-1α-Chitosan-Dextran Sulfate Nanoparticles
Published on: January 22, 2015
Synthesis and antioxidant properties of chitosan and carboxymethyl chitosan-stabilized selenium nanoparticles
Wanwen Chen1, Yanfang Li1, Shuo Yang1
1State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Lihu Road 1800, Wuxi 214122 Jiangsu, People's Republic of China.
Abstract:
Monodispersible selenium nanoparticles (SeNPs) were synthesized by using chitosan (CS) and carboxymethyl chitosan (CCS) as the stabilizer and capping agent using a facile synthetic approach. The structure, size, morphology and antioxidant activity of the nanocomposites were characterized by transmission electron microscopy (TEM), Ultraviolet-visible spectroscopy (UV-vis), Dynamic Light Scattering (DLS), Fourier transform infrared (FTIR), Thermogravimetric analysis (TGA). The results revealed that the monodispersible SeNPs (mean particle size of about 50 nm) were ligated with CS and CCS to form nanocomposites in aqueous solution for at least 30 days, and for 120 days the nanoparticles increased to 180 nm or so in size. The DPPH scavenging ability of CS-SeNPs was higher than that of CCS-SeNPs, and could reach 93.5% at a concentration of 0.6 mmol/L. Moreover, SeNPs, CS-SeNPs and CCS-SeNPs exhibited a higher ABTS scavenging ability in comparison to Na2SeO3.
