Related Experiment Video
Updated: Apr 5, 2026
A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
Published on: July 20, 2022
Noninfectious Complications of Peritoneal Dialysis in Korean Children: A 26-Year Single-Center Study
Ji Eun Kim1,2, Se Jin Park3, Ji Young Oh1,2
1Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Insights
Noninfectious complications are common in pediatric peritoneal dialysis (PD) patients but rarely necessitate catheter removal or switching to hemodialysis (HD). This study highlights the safety of PD in children, even with complications.
Area of Science:
- Pediatric Nephrology
- Renal Replacement Therapy
- Dialysis Complications
Background:
- Peritoneal dialysis (PD) is a crucial renal replacement therapy for pediatric end-stage renal disease.
- Understanding noninfectious complications is vital for optimizing PD management in children.
Purpose of the Study:
- To investigate the incidence and types of noninfectious complications in pediatric patients undergoing peritoneal dialysis.
- To assess the impact of these complications on treatment outcomes, including catheter survival and need for hemodialysis.
Main Methods:
- Retrospective analysis of data from 60 pediatric PD patients (aged ≤18 years) treated between 1986 and 2012.
- Data collection included patient demographics, causes of end-stage renal disease, and detailed records of noninfectious complications and their management.
Main Results:
- The most frequent cause of end-stage renal disease was glomerular disease (43.3%).
- Catheter-related complications included outflow failure (14.3%), leakage (10.0%), and hernia (8.6%).
- Metabolic complications like hyperglycemia and hypokalemia occurred in a small subset of patients; overall complication rates were comparable to prior pediatric studies.
Conclusions:
- Noninfectious complications are frequent in pediatric peritoneal dialysis but seldom lead to treatment cessation.
- Peritoneal dialysis remains a viable and safe long-term treatment option for children with end-stage renal disease, with minimal impact on catheter longevity or need for hemodialysis.
Purpose:
The aim of this study was to investigate noninfectious complications of peritoneal dialysis (PD), including mechanical and metabolic complications, at a single center in Korea.
Materials And Methods:
We analyzed data from 60 PD patients aged ≤18 years (40 boys and 20 girls) during the period between 1986 and 2012. The collected data included gender, age, causes of PD, incidence of noninfectious complications, and treatment for the complications.
Results:
The mean duration of PD therapy was 28.7±42.1 months (range 1-240 months). The most common cause of end-stage renal disease was glomerular disease (43.3%). There were no statistically significant differences between patients with and without mechanical complications regarding gender, age at the start of PD, and total duration of PD. Outflow failure was the most common catheter-related complication (14.3%), followed by leakage (10.0%) and hernia (8.6%). Metabolic complications, such as hyperglycemia and hypokalemia, were observed in three of 16 patients. The frequency of noninfectious complications of PD in our study was comparable with those in previous pediatric studies. PD was switched to hemodialysis (HD) in only three patients.
Conclusion:
Our results indicate that noninfectious complications of PD are common, though they hardly lead to catheter removal or HD in pediatric patients on PD.
Related Concept Videos
01:25Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
01:25Peritoneal Dialysis III: Nursing Management
01:24Hemodialysis II: Procedure and Complications
01:24Chronic Kidney Disease II: Clinical Manifestations
01:27Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
01:15Dialysis